Kabuki make-up syndrome associated with chronic idiopathic thrombocytopenic purpura.

TitleKabuki make-up syndrome associated with chronic idiopathic thrombocytopenic purpura.
Publication TypeJournal Article
Year of Publication1994
AuthorsWatanabe T, Miyakawa M, Satoh M, Abe T, Oda Y
JournalActa paediatrica Japonica; Overseas edition
Volume36
Issue6
Pagination727-9
Date Published1994 Dec
Abstract

Although susceptibility to infections in Kabuki make-up syndrome (KMS) has frequently been reported, there have been few immunological studies. We describe a 14 year old girl with KMS exhibiting chronic idiopathici thrombocytopenic purpurai (chronic ITPi), including immunological studies. Corticosteroid therapy was not effective therefore splenectomy was performed. The patient's platelet count increased transiently. Immunological studies revealed normal T cell functions and low serumi immunoglobulini A (IgA) levels. Because of the abnormalities of B cell functions in chronic ITP and low serum IgA levels in our patient, we speculate that there may be some abnormalities of humorali immunity in KMS.

Alternate JournalActa Paediatr Jpn
Citation Key7871993